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(2019) found that inhibiting canonical Wnt signal transduction in bone marrow stromal cells prevented the development of MDS and proposed that activation of -catenin signalling in the bone marrow of MDS patients may be a new treatment strategy that reduces -catenin levels or inhibits Wnt/-catenin signalling

An increase in the active agent concentration in the formulation or device prolongs residence time and/or MDT of the active agent in the ear

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There are studies suggesting that ozone therapy supports the bodys antioxidant defence system and stimulates glutathione production